Gil Ben-Horin
Published: Feb 16, 2017

A study performed in the NICU at Leiden University Medical Centre compared the effectiveness of an automated fraction of inspired oxygen (FiO2) system with manual titration of FiO2 in maintaining oxygen saturation (SpO2) within the intended target range. This is the first study that examines the impact of having automated FiO2 implemented in routine care for longer periods of time. The characteristics of each infant as well as clinical parameters and ventilator settings (including the FiO2 and SpO2) were sampled every minute and routinely collected in MetaVision. The authors conclude that implementation of automated FiO2 control led to an increased compliance of maintaining SpO2 within the intended target range during oxygen therapy, with the study results showing a significant decrease in hyperoxaemia, although no effect on hypoxaemia. The authors suggest that additional randomised studies be performed to confirm the beneficial effects of such automated oxygen control on the outcome for preterm infants.

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