A retrospective analysis Centre Hospitalier Universitaire Vaudois (CHUV) aimed to analyse the epidemiology, characteristics, and risk factors associated with Staphylococcus aureus early-onset pneumonia (EOP) to identify predictive factors that could be used to target it with early preemptive treatment, such as that using focused antibiotics or specific monoclonal antibodies. Data for all burn patients requiring more than four hours of mechanical ventilation who were admitted between January 2001 and October 2012 were extracted using MetaVision. The authors identified S. aureus carriage as an independent and strong predictor of EOP. They suggest that since rapid point of care testing for S. aureus is readily available, all patients should be tested at admission for burn trauma and early preemptive treatment should be considered for all positive patients, and note that further studies are needed to evaluate this new strategy.
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