Gil Ben-Horin
Published: Nov 16, 2016

A study performed at Leiden University Medical Center (LUMC) in the Netherlands studied oxygen saturation (SpO2) targeting before and after training and guideline implementation of manual oxygen titration by comparing two cohorts of preterm infants <30 weeks of gestation needing respiratory support and oxygen therapy. Respiratory support was given by a mechanical ventilator connected to the MetaVision patient data management system (PDMS), which supplied basic patient characteristics as well as clinical parameters every minute. The authors found that training guideline implementation in manual oxygen titration improved SpO2 targeting in preterm infants, with more time spent within the target range and less frequent hyperoxaemia. The durations of hypoxaemia and hyperoxaemia during ABCs (apnoea, bradycardia, cyanosis) were shorter. They conclude that, “This initiative in quality improvement had a positive effect, and if the observed reduction in the risk for hypoxaemia and hyperoxaemia could be maintained through repetitive training, it would be likely to improve the outcome of preterm infants.”

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