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Cumulative pain-related stress and developmental outcomes among low-risk preterm infants at one year corrected age

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Gil Ben-Horin
Published: Mar 16, 2017

A study examined the relationship between early pain-related stress (PRS) and neurodevelopmental outcomes among low-risk very preterm infants at the age of one year corrected age (CA). The authors hypothesised that increased cumulative exposure to pain would be associated with lower developmental scores. They found that among low-risk, invasive mechanical ventilation (IMV) preterm infants, increased exposure to PRS as measured by the NISS or SBP is directly and significantly associated with lower neurodevelopmental scores at 12.5 months CA. To the best of their knowledge, this is the first study that used both methods to study the correlation between PRS exposure and neurodevelopmental outcomes. Medical records from MetaVision, used in their neonatal department, served as a platform for collecting maternal and infant data.

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