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Gil Ben-Horin Published: Feb 16, 2017
A study performed at Johns Hopkins Hospital aimed to characterise the relationship between blood transfusion and different types of morbidity after posterior spine fusion by retrospectively analysing electronic medical records. The purpose of the study was to determine both if perioperative red blood cell (RBC) transfusion is associated with postoperative morbidity (including non-infectious complications) and if a dose-response relationship exists between transfusion and the likelihood of developing these complications. MetaVision was one of the systems that provided the necessary data for the study. To the authors’ knowledge, this is the first study to investigate non-infectious outcomes after spine fusion, and the relationship between transfusion and these complications. The data demonstrates risk-adjusted and transfusion dose-related increases in perioperative morbidity, with thrombotic and infectious events being the most common. The authors conclude that their findings offer new insights into the risk-benefit balance between anaemia, transfusion, and outcomes, and may help inform clinical decision-making, stating “By identifying transfusion as a risk factor for thrombosis and infections, our results may serve to heighten clinician awareness to optimise prevention, diagnosis, and treatment of these complications and thereby improve outcomes after spinal fusion.”
Gil Ben-Horin Jacob Krygier is a Clinical Application Specialist at iMDsoft with 20 years of hands-on healthcare experience. His background spans operating rooms, intensive care units, emergency medicine, and medivac air ambulances, with specialized expertise in anesthesia and emergency care.
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