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Gil Ben-Horin Published: Jul 16, 2016
A study performed at Institut Paoli-Calmettes in France evaluated the effects of ICU-related events, including the severity of acute respiratory distress syndrome (ARDS), on the long-term outcomes of haematology patients whose lungs required invasive mechanical ventilation. The authors also wanted to identify early predictive factors (during the first 48 hours of ICU admission) for developing moderate to severe ARDS. They prospectively studied all consecutive patients with haematological malignancy who were admitted to their ICU and required invasive mechanical ventilation for more than 24 hours over a five-year period. All data was extracted from MetaVision. This study is believed by the authors to be the first to evaluate long-term outcomes in patients with haematological malignancies who required ICU admission. The study results confirm that ICU mortality remains particularly high in the haematological population when invasive mechanical ventilation is required and that the extent of pulmonary infiltration observed on the first chest X-ray and the diagnosis of invasive fungal infection were the most relevant early predictive factors of the severity of ARDS. The authors conclude that high-risk patients may be identified early, simply by performing a chest X-ray upon ICU admission, and that prompt microbiological identification and targeted therapy should be a major objective of physicians toward improving outcomes.
Gil Ben-Horin Jacob Krygier is a Clinical Application Specialist at iMDsoft with 20 years of hands-on healthcare experience. His background spans operating rooms, intensive care units, emergency medicine, and medivac air ambulances, with specialized expertise in anesthesia and emergency care.
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