Home | Academic research | Protective effect of early low-dose hydrocortisone on ventilator-associated pneumonia (VAP) in the cancer patients: a propensity score analysis

Protective effect of early low-dose hydrocortisone on ventilator-associated pneumonia (VAP) in the cancer patients: a propensity score analysis

Back to lobby

Table of Contents

Gil Ben-Horin
Published: Oct 16, 2017

A study performed at Paoli-Calmettes Institute proposed that a low dose of hydrocortisone could help with modulation of immune response in the critically ill population. The authors reported on 190 onco-haematology patients admitted to the ICU and treated with mechanical ventilation over four years. To their knowledge, this is the first study reporting prognosis data with regard to VAP specifically in the cancer population. All data were extracted and analysed by senior physicians from MetaVision ICU. The authors found a positive effect of early low-dose hydrocortisone treatment in preventing VAP and conclude that “Critically ill cancer patients could benefit from the administration of low-dose hydrocortisone in the days surrounding mechanical ventilation initiation. This interesting result should be evaluated in a future large-scale randomized controlled trial.”

Back to lobby