A study performed at Johns Hopkins Hospital sought to define the impact of delta hemoglobin (ΔHb) relative to nadir Hb levels on the likelihood of transfusion, as well as characterise the impact of ΔHb and nadir Hb on morbidity among a large cohort of patients undergoing complex hepatopancreatobiliary (HPB) surgery. The authors identified patients who underwent pancreatic or hepatic resection between January 1, 2009 and June 30, 2015 and obtained and analysed data on the perioperative ΔHb, nadir Hb and blood utilisation, using the MetaVision automated anaesthesia information management system to extract data on intraoperative transfusion and Hb. The authors found that the combination of the Hb trigger with ΔHb was associated with transfusion practices among providers and that larger ΔHb values, as well as receipt of transfusion, were strongly associated with risk of perioperative complication following HPB surgery. They conclude that “Collectively, the data strongly suggest that the combination of the Hb trigger with ΔHb is likely the preferred manner to assess transfusion practices among providers, as well as identify patients at risk for postoperative complications.”

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